Free Download Goodman & Gilman's The Pharmacological Basis Of Therapeutics PDF
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Preface
The first edition of Goodman & Gilman, published in 1941, helped to organize the field of pharmacology, giving it intellectual validity and an academic identity. That edition began: “The subject of pharmacology is a broad one and embraces the knowledge of the source, physical and chemical properties, compounding, physiological actions, absorption, fate, and excretion, and therapeutic uses of drugs. A drug may be broadly defined as any chemical agent that affects living protoplasm, and few substances would escape inclusion by this definition.”
Introduction
Use of the term invention to describe the process by which a new drug is identified and brought to medical practice, rather than the more conventional term discovery, is intentional. Today, useful drugs are rarely discovered hiding somewhere waiting to be found. The term invention emphasizes the process by which drugs are sculpted and brought into being based on experimentation and optimization of many independent properties, there is little serendipity.
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